Relevant Preclinical Models

Patient derived xenograft (PDX) tumor models emerged as a new approach for preclinical testing of novel anticancer compounds in vivo due to its preservation of key features, which includes invasiveness, stromal reaction, tumor vasculature and cellular diversity of human carcinomas. In contrast to a cell line-xenograft tumor model, PDX tumors are established from the transplantation of fresh tumor tissue from a cancer patient into a immunodeficient mouse.

Below you will find a sample of our PDX models available through the core facility. Our repository also maintains over 30 additional PDX models that have shown consistent growth and have retained the histological characteristics of the patient tumor.

For more information, please submit a PDX Consultation request.