List of Publications

2024

  1. Cannon, Mark, et al. Cancer Cell Line Inhibition by Osmotic Pump administered Xylitol in a Syngeneic Mouse Model. https://doi.org/10.21203/rs.3.rs-3977059/v1
    SPACE
  2. Dolberg, Taylor B., et al. Building Synthetic Biosensors Using Red Blood Cell Proteins. ACS Synth. Biol. 2024, 13, 1273−1289. https://doi.org/10.1021/acssynbio.3c00754
    SPACE
  3. Hu, Ziying, et al. “Bioresorbable Multilayer Organic–Inorganic Films for Bioelectronic Systems.” Advanced Materials., 2024, https://doi.org/10.1002/adma.202309421
    SPACE
  4. Hu, Ziying, et al. “Ultrathin, Transferred Layers of Silicon Oxynitrides as Tunable Biofluid Barriers for Bioresorbable Electronic Systems.” Advanced Materials., 2024, https://doi.org/10.1002/adma.202307782
    SPACE
  5. Wang, Yinu. et al. Preclinical evaluation of NTX-301, a Novel DNA Hypomethylating Agent in Ovarian Cancer. Clin Cancer Res (2024). https://doi.org/10.1158/1078-0432.CCR-23-2368
    SPACE
  6. Wang, Yinu. et al. Nanoparticle Targeting in Chemo-Resistant Ovarian Cancer Reveals Dual Axis of Therapeutic Vulnerability Involving Cholesterol Uptake and Cell Redox Balance. Adv. Sci. 2024, 11, 2305212. https://doi.org/10.1002/advs.202305212
    SPACE
  7. Liu, Jiaqi. et al. Bioresorbable shape-adaptive structures for ultrasonic monitoring of deep-tissue homeostasis. Science 383, 1096–1103 (2024), https://doi.org/10.1126/science.adk9880

2023

  1. Alipourgivi F, Motolani A, Qiu AY, Qiang W, Yang G-Y, Chen S, Lu T. Genetic Alterations of NF-κB and Its Regulators: A Rich Platform to Advance Colorectal Cancer Diagnosis and Treatment. International Journal of Molecular Sciences. 2024; 25(1):154. https://doi.org/10.3390/ijms25010154
    SPACE
  2. Galat, Y. et al. In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies. Oncoimmunology 12, 2240670 (2023). https://doi.org/10.1080/2162402X.2023.2240670
    SPACE
  3. Huang Z-L, Abdallah AS, Shen G-X, Suarez M, Feng P, Yu Y-J, Wang Y, Zheng S-H, Hu Y-J, Xiao X, Li, X-N. et al. Silencing GMPPB Inhibits the Proliferation and Invasion of GBM via Hippo/MMP3 Pathways. International Journal of Molecular Sciences. 2023; 24(19):14707. https://doi.org/10.3390/ijms241914707
    SPACE
  4. Huang Z-L, Abdallah AS, Shen G-X, Suarez M, Feng P, Yu Y-J, Wang Y, Zheng S-H, Hu Y-J, Xiao X, Li, X-N. et al. Silencing GMPPB Inhibits the Proliferation and Invasion of GBM via Hippo/MMP3 Pathways. International Journal of Molecular Sciences. 2023; 24(19):14707. https://doi.org/10.3390/ijms241914707
    SPACE
  5. Ouyang, W., Lu, W., Zhang, Y., Liu, Y., Kim, J. U., Shen, H., Wu, Y., Luan, H., Kilner, K., Lee, S., Lu, Y., Yang, Y., Wang, J., Yu, Y., Wegener, A., Moreno, J., Xie, Z., Wu, Y., Won, S. M., Kwon, K., Wu, C., Bai, W., Guo, H., Liu, T., Bai, H., Monti, G., Zhu, J., Madhvapathy, S., Trueb, J., Stanslaski, M., Higbee-Dempsey, E., Stepien, I., Ghoreishi-Haack, N., Haney, C., Kim, T., Huang, Y., Ghaffari, R., Banks, A., Jhou, T., Good, C., Rogers, J. A. (2023).  A wireless and battery-less implant for multimodal closed-loop neuromodulation in small animals.  Nat Biomed Eng (2023).  https://doi.org/10.1038/s41551-023-01029-x.  April 2023
    SPACE
  6. Zhang, Y., Liu, F., Zhang, Y., Wang, J., D’Andrea, D., Walters, J. B., Li, S., Yoon, H. J., Wu, M., Li, S., Hu, Z., Wang, T., Choi, J., Bailey, K., Dempsey, E., Zhao, K., Lantsova, A., Bouricha, Y., Huang, I., Guo, H., Ni, X., Wu, Y., Lee, G., Jiang, F., Huang, Y., Franz, C. K., Rogers, J. A. (2023). Self-powered, light-controlled, bioresorbable platforms for programmed drug delivery.  PNAS 120 (11) e2217734120.  https://doi.org/10.1073/pnas.2217734120.  March 2023
    SPACE
  7. Zhang, Y., Wang, Y., Valdivia, A., Huang, H., Matei, D. (2023).  DOT1 L Regulates Ovarian Cancer Stem Cells by Activating β-catenin Signaling.  Mol Cancer Res (2023) 21 (2): 140–154.  https://doi.org/10.1158/1541-7786.MCR-22-0418.
    SPACE
  8. Zhang, H., Li, X., et al. Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models. J Transl Med 21, 444 (2023). https://doi.org/10.1186/s12967-023-04237-w February 2023

2022

  1. Bose, S., Li, X., et al. A path to translation: How 3D patient tumor avatars enable next generation precision oncology. Cancer Cell 40, 1448-1453 (2022). https://doi.org/10.1016/j.ccell.2022.09.017
    SPACE
  2. Choi, Y. S., Jeong, H., Yin, R. T., Avila, R., Pfenniger, A., Yoo, J., Lee, J. Y., Tzavelis, A., Lee, Y. J., Chen, S. W., Knight, H. S., Kim, S., Ahn, H. Y., Wickerson, G., Vázquez-Guardado, A., Higbee-Dempsey, E., Russo, B. A., Napolitano, M. A., Holleran, T. J., Razzak, L. A., Miniovich, A. N., Lee, G., Geist, B., Kim, B., Han, S., Brennan, J. A., Aras, K., Kwak, S. S., Kim, J., Waters, E. A., Yang, X., Burrell, A., Chun, K. S., Liu, C., Wu, C, Rwei, A. Y., Spann, A.N., Banks, A., Johnson, D., Zhang, Z.J., Haney, C. R., Jin, S. H., Sahakian, A. V., Huang, Y., Trachiotis, G. D., Knight, B. P., Arora, R. K., Efimov, I. R., Rogers, J. A. (2022). A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy.  Science 376, 1006. https://doi.org/10.1126/science.abm1703.  May 2022
    SPACE
  3. Guo, H., Bai, W., Ouyang, W., Liu, Y., Wu, C., Xu, Y., Weng, Y., Zang, H., Liu, Y., Jacobson, L., Hu, Z., Wang, Y., Arafa, H. M., Yang, Q, Lu, D., Li, S., Zhang, L., Xiao, X., Vázquez-Guardado, A., Ciatti, J., Dempsey, E., Ghoreishi-Haack, N., Waters, E. A., Haney, C. R., Westman, A. M., MacEwan, M. R., Pet, M. A., Rogers, J. A.  (2022).  Wireless Implantable Optical Probe for Continuous Monitoring of Oxygen Saturation in Flaps and Organ Grafts.  Nat Commun 13, 3009. https://doi.org/10.1038/s41467-022-30594-z.  May 2022
    SPACE
  4. Huang, I., Zhang, Y., Arafa, H. M., Li, S., Vazquez-Guardado, A., Ouyang, W., Liu, F., Madhvapathy, S., Song, J. W., Tzavelis, A., Trueb, J., Choi, Y., Jeang, W. J., Forsberg, V., Higbee-Dempsey, E., Ghoreishi-Haack, N., Stepien, I., Bailey, K., Han, S., Zhang, Z. J., Good, C., Huang, Y., Bandodkar, A., Rogers, J. A. (2022). High performance dual-electrolyte magnesium-iodine batteries that can harmlessly resorb in the environment or in the body. Energ Environ Sci 15(10), 4095-4108. https://doi.org/10.1039/d2ee01966c September 2022
    SPACE
  5. Lee, G., Ray, E., Yoon, H. J., Genovese, S., Choi, Y. S., Lee, M. K., Şahin, S., Yan, Y., Ahn, H. Y., Bandodkar, A. J., Kim, J., Park, M., Ryu, H., Kwak, S. S., Jung, Y. H., Odabas, A., Khandpur, U., Ray, W. Z., MacEwan, M. R., & Rogers, J. A. (2022). A bioresorbable peripheral nerve stimulator for electronic pain block. Science Advances, 8(40), [eabp9169]. https://doi.org/10.1126/sciadv.abp9169. October 2022
    SPACE
  6. Li, J., Li, X-N. et al. Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma. Sci Adv 6 (2020). https://doi.org/10.1126/sciadv.abb5427
    SPACE
  7. Li, J., Li, X-N. et al., Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma.Sci. Adv.6,eabb5427(2020). https://doi.org/10.1126/sciadv.abb5427
    SPACE
  8. Patino, C. A., Mukherjee, P., Berns, E. J., Moully, E. H., Stan, L., Mrksich, M., and Espinosa, H. D. (2022).  High-Throughput Microfluidics Platform for Intracellular Delivery and Sampling of Biomolecules from Live Cells.  ACS Nano 2022 16 (5), 7937-7946.  https://doi.org/10.1021/acsnano.2c00698.  May 2022
    SPACE
  9. Qi, L., Li, X-N. et al. Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo- and radiation therapies. Lab Invest 102, 185-193 (2022). https://doi.org/10.1038/s41374-021-00700-8
    SPACE
  10. Smith, R., Takagishi, S. R., Amici, D. R., Metz, K., Gayatri, S., Alasady, M. J., Wu, Y., Brockway, S., Taiberg, S. L., Khalatyan, N., Taipale, M., Santagata, S., Whitesell, L., Lindquist, S., Savas, J. N., Mendillo, M. L. (2022). HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state. Science Advances, 8(11). https://doi.org/10.1126/sciadv.abj6526.  March 2022
    SPACE
  11. Y., Li. J., Zhao, G., Huang, K-C., Cardenas, H., Wang, Y., Matei, D., Cheng, J-X. Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells. Nat Commun 13, 4554 (2022). https://doi.org/10.1038/s41467-022-32101-w.  August 2022
    SPACE
  12. Vidimar, V., Park, M., Stubb, CK., Ingram, NK., Qiang, W., Zhang, S. Gursel , D., Melnyk, RA., Satchell. KJF.  (2022). Proteolytic pan-RAS Cleavage Leads to Tumor Regression in Patient-derived Pancreatic Cancer Xenografts. Mol Cancer Ther 2022; 21:810–20. https://doi.org/10.1158/1535-7163.MCT-21-0550
    SPACE
  13. Yang, Q., Liu, T. L., Xue, Y., Wang, H., Xu, Y., Emon, B., Wu, M., Rountree, C., Wei, T., Kandela, I. K., Haney, C. R., Brikha, A., Stepien, I., Hornick, J. E., Sponenburg, R. A., Cheng, C., Ladehoff, L., Chen, Y., Hu, Z., Wu, C., Han, M., Torkelson, J. M., Kozorovitskiy, Y., Saif, M. T. A., Huang, Y., Chang, J-K., Rogers, J. A. (2022). Ecoresorbable and bioresorbable microelectromechanical systems. Nat Electron 5(8), 526-538. https://doi.org/10.1038/s41928-022-00791-1. July 2022
    SPACE
  14. Zhang, Q., Cai, Z., Gerratana, L., Davis, A. A., D’Amico, P., Jacob, S., Zhang, Y., Qiang, W., Behdad, A., Reduzzi, C., Manai, M., Flaum, L., Shah, A. N., Gradishar, W. J., Cristofanilli, M. (2022).  Efficacy of Baseline Circulating Tumor Cells (CTCs) and Circulating Tumor DNA (ctDNA) for Evaluation of Tumor Heterogeneity and Clinical Outcome in Advanced Breast Cancer.  Online preprint: http://dx.doi.org/10.2139/ssrn.4218806.  September 2022
    SPACE
  15. Zhao, S., Li, J., Zhang, H., Li, X-N. et al. Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas. Nat Commun 13, 6689 (2022). https://doi.org/10.1038/s41467-022-34514-z
    SPACE
  16. Zhou, Y., Han, C., Wang, E., Lorch, A. H., Serafin, V., Cho, B. K., Gutierrez Diaz, B. T., Calvo, J., Fang, C., Khodadadi-Jamayran, A., Tabaglio, T., Marier, C., Kuchmiy, A., Sun, L., Yacu, G., Filip, S. K., Jin, Q., Takahashi, Y. H., Amici, D. R., Rendleman, E. J., Rawat, R. Bresolin, S., Paganin, M., Zhang, C., Li, H., Kandela, I., Politanska, Y., Abdala-Valencia, H., … & Ntziachristos, P. (2020).  Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.  Cancer Discovery, 10: 1388-409. https://doi.org/10.1158/2159-8290.CD-19-1436.  September 2020

2021

  1. Adams, C. J., & Meade, T. J. (2021). Towards Imaging Pt Chemoresistance Using Gd(III)-Pt(II) Theranostic MR Contrast Agents. ChemMedChem, 16(24), 3663–3671. https://doi.org/10.1002/cmdc.202100389. December 2021
    SPACE
  2. Bai, W., Irie, M., Liu, Z., Luan, H., Franklin, D., Nandoliya, K., Guo, H., Zang, H., Weng, Y., Lu, D., Wu, D., Wu, Y., Song, J., Han, M., Song, E., Yang, Y., Chen, X., Zhao, H., Lu, W., Monti, G., Stepien, I., Kandela, I., Haney, C., Wu, C., Won, S. M., Ryu, H., Rwei, A., Shen, H., Kim, J., Yoon, H. J., Ouyang, W., Liu, Y., Suen, E., Chen, H., Okina, J., Liang, J., Huang, Y., Ameer, G. A., Zhou, W., & Rogers, J. A. (2021).  Bioresorbable Multilayer Photonic Cavities as Temporary Implants for Tether-Free Measurements of Regional Tissue Temperatures.  BME Frontiers, 2021, 8653218.  https://doi.org/10.34133/2021/8653218.  January 2021.
    SPACE
  3. Burbulla, L. F., Zheng, J., Song, P., Jiang, W., Johnson, M. E., Brundin, P., & Krainc, D. (2021). Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson’s disease models. JCI insight, 6(19), e148649. https://doi.org/10.1172/jci.insight.148649. October 2021
    SPACE
  4. D’Amico, P., Reduzzi, C., Qiang, W., Zhang, Y., Gerratana, L., Zhang, Q., Davis, A. A., Shah, A. N., Manai, M., Curigliano, G., & Cristofanilli, M. (2021). Single-Cells Isolation and Molecular Analysis: Focus on HER2-Low CTCs in Metastatic Breast Cancer. Cancers, 14(1), 79. https://doi.org/10.3390/cancers14010079. December 2021
    SPACE
  5. Elghetany, M.T., Ho, JM., Shi-Qi, L.H., Li, X-N., et al. Maximizing the potential of aggressive mouse tumor models in preclinical drug testing. Sci Rep 11, 11580 (2021). https://doi.org/10.1038/s41598-021-91167-6
    SPACE
  6. Fischietti, M., Eckerdt, F., Blyth, G. T., Arslan, A. D., Mati, W. M., Oku, C. V., Perez, R. E., Lee-Chang, C., Kosciuczuk, E. M., Saleiro, D., Beauchamp, E. M., Lesniak, M. S., Verzella, D., Sun, L., Fish, E. N., Yang, G. Y., Qiang, W., & Platanias, L. C. (2021). Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma. Oncogene, 40(18), 3273–3286. https://doi.org/10.1038/s41388-021-01761-1. April 2021.
    SPACE
  7. Galat, Y., Gu, H., Perepitchka, M., Taylor, R., Yoon, J.W., Glukhova, X. A., Li, X-N., Beletsky, I. P., Walterhouse, D. O., Galat, V., Iannaccone, .P. M.,  CRISPR editing of the GLI1 first intron abrogates GLI1 expression and differentially alters lineage commitment, Stem Cells, Volume 39, Issue 5, May 2021, Pages 564–580, https://doi.org/10.1002/stem.3341
    SPACE
  8. Guo, H., D’Andrea, D., Zhao, J., Xu, Y., Qiao, Z., Janes, L. E., Murthy, N. K., Li, R., Xie, Z., Song, Z., Meda, R., Koo, J., Bai, W., Choi, Y. S., Jordan, S. W., Huang, Y., Franz, C. K., Rogers, J. A. (2021). Advanced Materials in Wireless, Implantable Electrical Stimulators that Offer Rapid Rates of Bioresorption for Peripheral Axon Regeneration.  Adv Func Mater, 2021, 31, 2102724. https://doi.org/10.1002/adfm.202102724.  May 2021.
    SPACE
  9. Lu, W., Bai, W., Zhang, H., Xu, C., Chiarelli, A. M., Vasquez-Guardado, A., Xie, Z., Shen, H., Nandoliya, K., Zhao, H., Lee, K., Wu, Y., Franklin, D., Avila, R., Xu, S., Rwei, A., Han, M., Kwon, K., Deng, Y., Yu, X., Thorp, E. B., Feng, X., Huang, Y., Forbess, J., Ge, Z. D., & Rogers, J. A., (2021). Wireless, implantable catheter-type oximeter designed for cardiac oxygen saturation. Science Advances, 7(7).  https://doi.org/10.1126/sciadv.abe0579  February 2021.
    SPACE
  10. Miodragović, Ð., Qiang, W., Sattar Waxali, Z., Vitnik, Ž., Vitnik, V., Yang, Y., Farrell, A., Martin, M., Ren, J., & O’Halloran, T. V. (2021). Iodide Analogs of Arsenoplatins-Potential Drug Candidates for Triple Negative Breast Cancers. Molecules (Basel, Switzerland), 26(17), 5421. https://doi.org/10.3390/molecules26175421. September 2021.
    SPACE
  11. Shaik, S., Maegawa, S., Haltom, A. R., Wang, F., Xiao, X., Dobson, T., Sharma, A., Yang, Y., Swaminathan, J., Kundra, V., Li, X. N., Schadler, K., Harmanci, A., Xu, L., & Gopalakrishnan, V. (2021). REST promotes ETS1‐dependent vascular growth in medulloblastoma. Molecular Oncology., 15(5), 1486–1506. https://doi.org/10.1002/1878-0261.12903
    SPACE
  12. Srivastava, S., Sahu, U., Zhou, Y., Hogan, A. K., Sathyan, K. M., Bodner, J., Huang, J., Wong, K. A., Khalatyan, N., Savas, J. N., Ntziachristos, P., Ben-Sahra, I., & Foltz, D. R. NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia.  Science Advances, 7(5).  https://doi.org/10.1126/sciadv.abc9781.  January 2021.
    SPACE
  13. Vassal, G. Li, X. N., et al. International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer. Mol Cancer Ther 20, 1462-1468 (2021). https://doi.org/10.1158/1535-7163.MCT-20-0394
    SPACE
  14. Villa, E., Sahu, U., O’Hara, B. P., Ali, E. S., Helmin, K. A., Asara, J. M., Gao, P., Singer, B. D., & Ben-Sahra, I. (2021).  mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.  Molecular Cell, 81(10):2076-2093.  https://doi.org/10.1016/j.molcel.2021.03.009.  March 2021
    SPACE
  15. Wang, Y., Zhao, G., Condello, S., Huang, H., Cardenas, H., Tanner, E. J., Wei, J., Yanrong, J., Li, J., Tan, Y., Davuluri, R. V., Peter, M. E., Cheng, J. X., & Matei, D. (2021). Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis. Cancer Research, 81(2). https://doi.org/10.1158/0008-5472.CAN-20-1488. January 2021.
    SPACE
  16. Wang, Y. et al. Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis. Cancer Res 81, 384-399 (2021). https://doi.org/10.1158/0008-5472.CAN-20-1488
    SPACE
  17. Yang, Y., Wu, M., Vázquez-Guardado, A., Wegener, A. J., Grajales-Reyes, J. G., Deng, Y., Wang, T., Avila, R., Moreno, J. A., Minkowicz, S., Dumrongprechachan, V., Lee, J., Zhang, S., Legaria, A. A., Ma, Y., Mehta, S., Franklin, D., Hartman, L., Bai, W., Han, M., Zhao, H., Lu, W., Yu, Y., Sheng, X., Banks, A., Yu, X., Donaldson, Z. R., Gereau, R. W., Good, C. H., Xie, Z., Huang, Y., Kozorovitskiy, Y., Rogers, J. A. Wireless multilateral devices for optogenetic studies of individual and social behaviors. Nat Neurosci24, 1035–1045 (2021). https://doi.org/10.1038/s41593-021-00849-x. May 2021.
    SPACE
  18. Yang, Q., Wei, T., Yin, R., Wu, M., Xu, Y., Koo, J., Choi, Y. S., Xie, Z., Chen, S., Kandela, I., Yao, S., Deng, Y., Avila, R., Liu, T. L., Bai, W., Yang, Y., Han, M., Zhang, Q., Haney, C., Lee, K. B., Aras, K., Wang, T., Seo, M. H., Luan, H., Lee, S. M., Brikha, A., Ghoreishi-Haack, N., Tran, L., Stepien, I., Aird, F., Waters, E., Yu, X., Banks, A., Trachiotis, G., Torkelson, J., Huang, Y., Kozorovitskiy, Y., & Rogers, J. A. (2021).  Photocurable, bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues.  Nature Materials, 20:1559-1570.  https://doi.org/10.1038/s41563-021-01051-x.  July 2021

2020

  1. Albarqi, H. A., Demessie, A. A., Sabei, F. Y., Moses, A. S., Hansen, M. N., Dhagat, P., Taratula, O. R., Taratula, O. (2020). Systemically Delivered Magnetic Hyperthermia for Prostate Cancer Treatment. Pharmaceutics, 12(11): 1020. https://doi.org/10.3390/pharmaceutics12111020. November 2020.
    SPACE
  2. Baxter, P.A., Su, J.M., Onar-Thomas, A, Billups, C.A., Li, X., Poussaint, T.Y., Smith, E.R., Thompson, P., Adesina, A., Ansell, P., Giranda, V.,  Paulino,A.,  Kilburn, L., Quaddoumi, I.,  Broniscer, A., Blaney, S.M., Dunkel, I.J.,  Fouladi, M., A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study, Neuro-Oncology, Volume 22, Issue 6, June 2020, Pages 875–885, https://doi.org/10.1093/neuonc/noaa016
    SPACE
  3. Burton, A., Obaid, S. N., Vázquez-Guardado, A., Schmit, M. B., Stuart, Cai, L., Chen, Z., Kandela, I., Haney, C., Waters, E. A., Cai, H., Rogers, J. A., Lu, L., & Gutruf, P. (2020). Wireless, battery-free subdermally implantable photometry systems for chronic recording of neural dynamics. Proceedings of the National Academy of Sciences, 117(6), 2835-2845. https://doi.org/10.1073/pnas.1920073117. January 2020
    SPACE
  4. Chen, X., Cates, J. M. M., Du, Y.-C., Jain, A., Jung, S. Y., Li, X.-N., Hicks, J. M., & Man, T. (2020). Mislocalized cytoplasmic p27 activates PAK1‐mediated metastasis and is a prognostic factor in osteosarcoma. Molecular Oncology., 14(4), 846–864. https://doi.org/10.1002/1878-0261.12624
    SPACE
  5. Choi, Y. S., Hsueh, Y. Y., Koo, J., Yang, Q., Avila, R., Hu, B., Xie, Z., Lee, G., Ning, Z., Liu, C., Xu, Y., Lee, Y. J., Zhao, W., Fang, J., Deng, Y., Lee, S. M., Vasquez-Guardado, A., Stepien, I., Yan, Y., Song, J. W., Haney, C., Oh, Y. S., Liu, W., Yoon, H. J., Banks, A., MacEwan, M. R., Ameer, G. A., Ray, W. Z., Huang, Y., Xie, T., Franz, S. L., & Rogers, J. A. (2020). Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration.  Nature Communications, 11, 5990. https://doi.org/10.1038/s41467-020-19660-6.  November 2020.
    SPACE
  6. Gerratana, L. et al. Performance of a novel Next Generation Sequencing circulating tumor DNA (ctDNA) platform for the evaluation of samples from patients with metastatic breast cancer (MBC). Crit Rev Oncol Hematol 145, 102856 (2020). https://doi.org/10.1016/j.critrevonc.2019.102856 Mukherjee, P., Berns, E. J., Patino, C. A., Moully, E. H., Chang, L., Nathamgari, S. S. P., Kessler, J. A., Mrksich, M., & Espinosa, H. D. (2020).  Temporal Sampling of Enzymes from Live Cells by Localized Electroporation and Quantification of Activity by SAMDI Mass Spectrometry.  Small, 16(26).  https://doi.org/10.1002/smll.202000584.  May 2020.
    SPACE
  7. Kamoun, W., Swindell, E., Pien, C., Luus, L., Cain, J., Pham, M., Kandela, I., Huang, Z. R., Tipparaju, S.K., Koshkaryev, A., Askoxylakis, V., Kirpotin, D. B., Bloom, T., Mino-Kenudson, M., Marks, J. D., Zalutskaya, A., Bshara, W., Morrison, C., & Drummond, D. C. (2020).  Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic. Pharmaceutics, 12(10):996. https://doi.org/10.1158/1538-7445.AM2018-5771.  October 2020.
    SPACE
  8. Li, Y., Qiang, W., Griffin, B. B., Gao, T., Chakravarti, D., Bulun, S., Kim, J. J., & Wei, J. J. (2020). HMGA2-mediated tumorigenesis through angiogenesis in leiomyoma. Fertility and sterility, 114(5), 1085–1096. https://doi.org/10.1016/j.fertnstert.2020.05.036. November 2020 
    SPACE
  9. Lu, D., Yan, Y., Avila, R., Kandela, I., Stepien, I., Seo, M. H., Bai, W., Yang, Q., Li, C., Haney, C. R., Waters, E. A., MacEwan, M. R., Huang, Y., Ray, W. Z., & Rogers, J. A. (2020). Bioresorbable, Wireless, Passive Sensors as Temporary Implants for Monitoring Regional Body Temperature. Advanced Healthcare Materials, 9(16), [2000942]. https://doi.org/10.1002/adhm.202000942. June 2020
    SPACE
  10. Modica, J. A., Iderzorig, T., & Mrksich, M. (2020).  Design and Synthesis of Megamolecule Mimics of a Therapeutic Antibody.  Am. Chem. Soc., 142, 32, 13657-13661.  https://doi.org/10.1021/jacs.0c05093.  July 2020
    SPACE
  11. Mukherjee, P., Berns, E. J., Patino, C. A., Hakim Moully, E., Chang, L., Nathamgari, S. S. P., Kessler, J. A., Mrksich, M., & Espinosa, H. D. (2020). Temporal Sampling of Enzymes from Live Cells by Localized Electroporation and Quantification of Activity by SAMDI Mass Spectrometry. Small : Nano Micro., 16(26). https://doi.org/10.1002/smll.202000584
    SPACE
  12. Qi, L., Li, X.-N. et al. Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors. Cancer Lett 493, 197-206 (2020). https://doi.org/10.1016/j.canlet.2020.08.035
    SPACE
  13. Rusert, J. M., Li, X.-N. et al. Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma. Cancer Res 80, 5393-5407 (2020). https://doi.org/10.1158/0008-5472.CAN-20-1655
    SPACE
  14. Sheibani, N., Zaitoun, I. S., Wang, S., Darjatmoko, S. R., Suscha, A., Song, Y. S., Sorenson C. M., Shifrin V., Albert D. M., Melgar-Asenio I., Kandela, I., & Henkin J. (2020). Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy. Experimental Eye Research, 108030. https://doi.org/10.1016/j.exer.2020.108030. June 2020
    SPACE
  15. Wang, F. et al. ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice. Gastroenterology 159, 289-305 e216 (2020). https://doi.org/10.1053/j.gastro.2020.03.013
    SPACE
  16. Yao, M., Li, X.-N. et al. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth. Cell 180, 502-520 e519 (2020). https://doi.org/10.1016/j.cell.2019.12.024
    SPACE
  17. Zhang, H., Li, X.-N. et al. Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma. Cancers (Basel) 12 (2020). https://doi.org/10.3390/cancers12061478
    SPACE
  18. Zhu, J.J., Jillette, N., Li, XN. et al. C11orf95-RELA reprograms 3D epigenome in supratentorial ependymoma. Acta Neuropathol 140, 951–960 (2020). https://doi.org/10.1007/s00401-020-02225-8

2019

  1. Bai, W., Shin, J., Fu, R., Kandela, I., Lu, D., Ni, X., … & Liu, Y. (2019). Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity. Nature biomedical engineering, 3(8), 644-654. https://doi.org/10.1038/s41551-019-0435-y. August 2019
    SPACE
  2. Battistella, C., Callmann, C. E., Thompson, M. P., Yao, S., Yeldandi, A. V., Hayashi, T., Carson, D. A., & Gianneschi, N. C. (2019). Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme‐Directed Assembly. Advanced Healthcare Materials., 8(23). https://doi.org/10.1002/adhm.201901105
    SPACE
  3. Bushnell, G. G., Hong, X., Hartfield, R. M., Zhang, Y., Oakes, R. S., Rao, S. S., Jeruss, J. S., Stegemann, J. P., Deng, C. X., & Shea, L. D. (2020).  High Frequency Spectral Ultrasound Imaging to Detect Metastasis in Implanted Biomaterial Scaffolds.  Annals of Biomedical Engineering, 48, 477-489.  https://doi.org/10.1007/s10439-019-02366-2.  September 2019
    SPACE
  4. Callmann, C. E., LeGuyader, C. L., Burton, S. T., Thompson, M. P., Hennis, R., Barback, C., … & Gianneschi, N. C. (2019). Antitumor Activity of 1, 18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin. Journal of the American Chemical Society, 141(30), 11765-11769. https://doi.org/10.1021/jacs.9b04272. July 2019
    SPACE
  5. Davis, A.A., Zhang, Q., Gerratana, L. et al. Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer. Breast Cancer Res 21, 137 (2019). https://doi.org/10.1186/s13058-019-1229-6
    SPACE
  6. Gerratana, L., Zhang, Q., Shah, A. N., Davis, A. A., Zhang, Y., Wehbe, F., Qiang, W., Flaum, L., Finkelman, B. S., Gradishar, W. J., Platanias, L. C., Behdad, A., & Cristofanilli, M. (2020). Performance of a novel Next Generation Sequencing circulating tumor DNA (ctDNA) platform for the evaluation of samples from patients with metastatic breast cancer (MBC). Critical reviews in oncology/hematology, 145, 102856. https://doi.org/10.1016/j.critrevonc.2019.102856. January 2019
    SPACE
  7. Han, H., Jain, A. D., Truica, M. I., Izquierdo-Ferrer, J., Anker, J. F., Lysy, B., Sagar, V., Luan, Y., Chalmers, Z. R., Unno, K., Mok, H., Vatapalli, R., Yoo, Y. A., Rodriguez, Y., Kandela, I., Parker, J. B., Chakravarti, D., Mishra, R. K., Schiltz, G. E., & Abdulkadir, S. A. (2019). Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer cell, 36(5), 483-497. https://doi.org/10.1016/j.ccell.2019.10.001. October 2019
    SPACE
  8. Han, M., Wang, H., Yang, Y., Liang, C., Bai, W., Yan, Z., Li, H., Xue, Y., Wang, X., Akar, B., Zhao, H., Luan, H., Lim, J., Kandela, I., Ameer, G. A., Zhang, Y., Huang, Y., & Rogers, J. A. (2019). Three-dimensional piezoelectric polymer microsystems for vibrational energy harvesting, robotic interfaces and biomedical implants. Nature Electronics, 2(1), 26-35. https://doi.org/10.1038/s41928-018-0189-7. Jan 2019 Jin, Q., Martinez, C. A., Arcipowski, K. M., Zhu, Y., Gutierrez-Diaz, B. T., Wang, K. K., … Kandela, I., … & Ntzuachristos, P. USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia. Clinical Cancer Research, 25(1), 222-239. https://doi.org/10.1158/1078-0432.ccr-18-1740. Jan 2019
    SPACE
  9. Hovestadt, V., Smith, K.S., Bihannic, L., Li, X-N. et al. Resolving medulloblastoma cellular architecture by single-cell genomics. Nature 572, 74–79 (2019). https://doi.org/10.1038/s41586-019-1434-6
    SPACE
  10. Lin, K. et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep 26, 2434-2450 e2436 (2019). https://doi.org/10.1016/j.celrep.2019.01.111 Lambo, S., Gröbner, S.N., Rausch, T. Li, X-N. et al. The molecular landscape of ETMR at diagnosis and relapse. Nature 576, 274–280 (2019). https://doi.org/10.1038/s41586-019-1815-x
    SPACE
  11. Rokita, J. L., Li, X-N. et al. Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. Cell Rep 29, 1675-1689 e1679 (2019). https://doi.org/10.1016/j.celrep.2019.09.071
    SPACE
  12. Romero-Calvo, I., Weber, CR., Ray, M., Brown, M., Kirby, K., Nandi, R., Long, T., Sparrow, S., Ugolkov, A., Qiang, W., Zhang, Y., Brunetti, T., Kindler, H., Segal, J., Rzhetsky, A., Mazar, A., Buschmann, M., Weichselbaum, R., Roggin, K., White, K. (2019). Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.  Mol Cancer Res (2019) 17 (1): 70–83 https://doi.org/10.1158/1541-7786.MCR-18-0531
    SPACE
  13. Sheibani, N., Wang, S., Darjatmoko, S. R., Fisk, D. L., Shahi, P. K., Pattnaik, B. R., Sorenson, C. M., Bhowmick, R., Volpert, O. V., Albert, D. M., Melgar-Asensio, I., & Henkin, J. (2019). Novel anti-angiogenic PEDF-derived small peptides mitigate choroidal neovascularization. Experimental eye research, 188, [107798]. https://doi.org/10.1016/j.exer.2019.107798. November 2019
    SPACE
  14. Shin, J. et al. Bioresorbable pressure sensors protected with thermally grown silicon dioxide for the monitoring of chronic diseases and healing processes. Nat Biomed Eng 3, 37-46 (2019). https://doi.org/10.1038/s41551-018-0300-4
    SPACE
  15. Shin, J., Liu, Z., Bai, W., Liu, Y., Yan, Y., Xue, Y., Kandela, I., Pezhouh, M., MacEwan, M. R., Huang, Y., Ray, W. Z., Zhou, W., & Rogers, J. A. (2019). Bioresorbable optical sensor systems for monitoring of intracranial pressure and temperature. Science Advances, 5(7), [eaaw1899]. https://doi.org/10.1126/sciadv.aaw1899. July 2019
    SPACE
  16. Sima, L. E., Yakubov, B., Zhang, S., Condello, S., Grigorescu, A. A., Nwani, N. G., … & Matei, D. (2019). Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin. Molecular cancer therapeutics, 18(6), 1057-1068. https://doi.org/10.1158/1535-7163.mct-18-1148. June 2019
    SPACE
  17. Sin-Chan, P., Li, X-N. et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell 36, 51-67 e57 (2019). https://doi.org/10.1016/j.ccell.2019.06.002
    SPACE
  18. Teo, W. Y., Li, X-N. et al. Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations. Sci Rep 9, 7442 (2019). https://doi.org/10.1038/s41598-019-43173-y
    SPACE
  19. Winkelmann, J.A., Eid, A., Spicer, G. et al. Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. Light Sci Appl 8, 7 (2019). https://doi.org/10.1038/s41377-018-0117-7
    SPACE
  20. Zhang, H., Gutruf, P., Meacham, K., Montana, M. C., Zhao, X., Chiarelli, A. M., Vázquez-Guardado8, A., Norris, A., Lu, L., Guo, Q., Xu, C., Wu, Y., Zhao, H., Ning, X., Bai, W., Kandela, I., Haney, C., Chanda, D., Gereau, R. W., & Rogers, J. A. (2019). Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry. Science Advances, 5(3), eaaw0873.  https://doi.org/10.1126/sciadv.aaw0873.  March 2019

2018 

  1. Bai W, Yang H, Ma Y, Chen H, Shin J, Liu Y, Yang Q, Kandela I, Liu Z, Kang SK, Wei C, Haney CR, Brikha A, Ge X, Feng X, Braun PV, Huang Y, Zhou W, Rogers JA. Flexible Transient Optical Waveguides and Surface-Wave Biosensors Constructed from Monocrystalline Silicon. Adv Mater. 2018 Aug;30(32):e1801584. https://doi.org/10.1002/adma.201801584. Epub 2018 Jun 26. PubMed PMID: 29944186.
    SPACE
  2. Dong H, Zhu M, Meng L, Ding Y, Yang D, Zhang S, Qiang W, Fisher DW, Xu EY. Pumilio2 regulates synaptic plasticity via translational repression of synaptic receptors in mice. Oncotarget. 2018 Jan 30;9(63):32134-32148. doi:10.18632/oncotarget.24345. eCollection 2018 Aug 14. PubMed PMID: 30181804; PubMed Central PMCID: PMC6114944.
    SPACE
  3. Frankowski KJ, Wang C, Patnaik S, Schoenen FJ, Southall N, Li D, Teper Y, Sun  W, Kandela I, Hu D, Dextras C, Knotts Z, Bian Y, Norton J, Titus S, Lewandowska MA, Wen Y, Farley KI, Griner LM, Sultan J, Meng Z, Zhou M, Vilimas T, Powers AS, Kozlov S, Nagashima K, Quadri HS, Fang M, Long C, Khanolkar O, Chen W, Kang J, Huang H, Chow E, Goldberg E, Feldman C, Xi R, Kim HR, Sahagian G, Baserga SJ, Mazar A, Ferrer M, Zheng W, Shilatifard A, Aubé J, Rudloff U, Marugan JJ, Huang S. Metarrestin, a perinucleolar compartment inhibitor, effectively suppressesmetastasis. Sci Transl Med. 2018 May 16;10(441). pii: eaap8307. doi:10.1126/scitranslmed.aap8307. PubMed PMID: 29769289.
    SPACE
  4. Huang W, Bei L, Eklund EA. Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin. Oncotarget. 2018 May 25;9(40):25891-25902. doi:10.18632/oncotarget.25401. eCollection 2018 May 25. PubMed PMID: 29899829; PubMed Central PMCID: PMC5995227.
    SPACE
  5. Li X, Schumann C, Albarqi HA, Lee CJ, Alani AWG, Bracha S, Milovancev M,Taratula O, Taratula O. A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy. Theranostics. 2018 Jan 1;8(3):767-784. doi:10.7150/thno.21209. eCollection 2018. PubMed PMID: 29344305; PubMed Central PMCID: PMC5771092.
    SPACE
  6. Melgar-Asensio I, Kandela I, Aird F, Darjatmoko SR, de Los Rios C, Sorenson CM, Albert DM, Sheibani N, Henkin J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4071-4081. doi:10.1167/iovs.18-24087. PubMed PMID: 30098194; PubMed Central PMCID: PMC6088811.
    SPACE
  7. Robinson EE, Thomson RJ. A Strategy for the Convergent and Stereoselective Assembly of Polycyclic Molecules. J Am Chem Soc. 2018 Feb 7;140(5):1956-1965. doi:10.1021/jacs.7b13234. Epub 2018 Jan 24. Erratum in: J Am Chem Soc. 2018 Jun 6;140(22):7043. PubMed PMID: 29309727.
    SPACE
  8. Romero-Calvo I, Weber C, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP. Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors. Mol Cancer Res. 2018 Aug 31. pii: molcanres.0531.2018. doi:10.1158/1541-7786.MCR-18-0531. [Epub ahead of print] PubMed PMID: 30171177.
    SPACE
  9. Serna VA, Wu X, Qiang W, Thomas J, Blumenfeld ML, Kurita T. Cellular kinetics of MED12-mutant uterine leiomyoma growth and regression in vivo. Endocr Relat Cancer. 2018 Jul;25(7):747-759. doi: 10.1530/ERC-18-0184. Epub 2018 Apr 26. PubMed PMID: 29700012; PubMed Central PMCID: PMC6032993.
    SPACE
  10. Shan X, Danet-Desnoyers G, Aird F, Kandela I, Tsui R, Perfito N, Iorns E. Replication study: androgen receptor splice variants determine taxane sensitivity in prostate cancer. PeerJ. 2018 Apr 16;6:e4661. doi: 10.7717/peerj.4661.
    SPACE
  11. Shin, J., Yan, Y., Bai, W., Xue, Y., Gamble, P., Tian, L., Kandela, I., Haney, C. R., Spees, W., Lee, Y., Choi, M., Ko, J., Ryu, H., Chang, J. K., Pezhouh, M., Kang, S. K., Won, S. M., Yu, K. J., Zhao, J., … & Rogers, J. A. (2019). Bioresorbable pressure sensors protected with thermally grown silicon dioxide for the monitoring of chronic diseases and healing processes. Nature Biomedical Engineering, 3(1), 37-46. https://doi.org/10.1038/s41551-018-0300-4. October 2018
    SPACE
  12. Uno BE, Deibler KK, Villa C, Raghuraman A, Scheidt KA. Conjugate Additiona of Amines to Maleimides via Cooperative Catalysis. Adv Synth Catal. 2018 Feb:360(8) 1719-1725. https://doi.org/10.1002/adsc.201800160

2017 

  1. Aird F, Kandela I, Mantis C; Reproducibility Project: Cancer Biology.. Replication Study: BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Elife. 2017 Jan 19;6. pii: e21253. https://doi.org/10.7554/eLife.21253. 
    SPACE
  2. Bell JB, Eckerdt F, Dhruv HD, Finlay D, Peng S, Kim S, Kroczynska B, Beauchamp EM, Alley K, Clymer J, Goldman S, Cheng SY, James CD, Nakano I, Horbinski C, Mazar AP, Vuori K, Kumthekar P, Raizer J, Berens ME, Platanias LC. Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation. Mol Cancer Res. 2018 Jan;16(1):32-46. doi:10.1158/1541-7786.MCR-17-0397. Epub 2017 Oct 17. PubMed PMID: 29042487; PubMed Central PMCID: PMC5926791.
    SPACE
  3. Hartlieb KJ, Ferris DP, Holcroft JM, Kandela I, Stern CL, Nassar MS, Botros YY, Stoddart JF. Encapsulation of Ibuprofen in CD-MOF and Related Bioavailability Studies. Mol Pharm. 2017 May 1;14(5):1831-1839. doi:10.1021/acs.molpharmaceut.7b00168. Epub 2017 Apr 12. PubMed PMID: 28355489.
    SPACE
  4. Hendrix MJ, Kandela I, Mazar AP, Seftor EA, Seftor RE, Margaryan NV, Strizzi L, Murphy GF, Long GV, Scolyer RA. Targeting melanoma with front-line therapy does not abrogate Nodal-expressing tumor cells. Lab Invest. 2017 Feb;97(2):176-186. doi: 10.1038/labinvest.2016.107. Epub 2016 Oct 24.
    SPACE
  5. Kandela I, Aird F; Reproducibility Project: Cancer Biology.. Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data. Elife. 2017 Jan 19;6. pii: e17044. doi:10.7554/eLife.17044.
    SPACE
  6. Kandela IK, McAuliffe KJ, Cochran LE, Barrett AGM, Hoffman BM, Mazar AP, Trivedi ER. Discovery of the Antitumor Effects of a Porphyrazine Diol (Pz 285) in MDA-MB-231 Breast Tumor Xenograft Models in Mice. ACS Med Chem Lett. 2017 Jun 29;8(7):705-709. doi: 10.1021/acsmedchemlett.7b00063. eCollection 2017 Jul 13. PubMed PMID: 28740602; PubMed Central PMCID: PMC5512131.
    SPACE
  7. Liu Y, Lou G, Norton JT, Wang C, Kandela I, Tang S, Shank NI, Gupta P, Huang M, Avram MJ, Green R, Mazar A, Appella D, Chen Z, Huang S. 6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib. FASEB J. 2017 Dec;31(12):5453-5465. https://doi.org/10.1096/fj.201700306RR. Epub 2017 Aug 17. PubMed PMID:28821631; PubMed Central PMCID: PMC5690379.
    SPACE
  8. Mantis C, Kandela I, Aird F; Reproducibility Project: Cancer Biology.. Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Elife. 2017 Jan 19;6. pii: e17584. doi:10.7554/eLife.17584.
    SPACE
  9. Ugolkov A, Qiang W, Bondarenko G, Procissi D, Gaisina I, James CD, Chandler J, Kozikowski A, Gunosewoyo H, O’Halloran T, Raizer J, Mazar AP. Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models. Transl Oncol. 2017 Aug;10(4):669-678. doi: 10.1016/j.tranon.2017.06.003. Epub 2017 Jun 30. PubMed PMID: 28672195; PubMed Central PMCID: PMC5496477.

2016 

  1. He C, Poon C, Chan C, Yamada SD, Lin W. Nanoscale Coordination Polymers Codeliver Chemotherapeutics and siRNAs to Eradicate Tumors of Cisplatin-Resistant Ovarian Cancer. J Am Chem Soc. 2016 May 11;138(18):6010-9. doi:10.1021/jacs.6b02486. Epub 2016 May 2. PubMed PMID: 27088560; PubMed Central PMCID: PMC5668688
    SPACE
  2. Poon C, Duan X, Chan C, Han W, Lin W. Nanoscale Coordination Polymers Codeliver Carboplatin and Gemcitabine for Highly Effective Treatment of Platinum-Resistant Ovarian Cancer. Mol Pharm. 2016 Nov 7;13(11):3665-3675. https://doi.org/10.1021/ACS.MOLPHARMACEUT.6B00466. Epub 2016 Oct 21. PubMed PMID: 27712076; PubMed Central PMCID: PMC5673481. 
    SPACE
  3. Rao SS, Bushnell GG, Azarin SM, Spicer G, Aguado BA, Stoehr JR, Jiang EJ, Backman V, Shea LD, Jeruss JS. Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo. Cancer Res. 2016 Sep 15;76(18):5209-18. doi: 10.1158/0008-5472.CAN-15-2106. PubMed PMID: 27635043; PubMed Central PMCID: PMC5027988.
    SPACE
  4. Rammohan N, MacRenaris KW, Moore LK, Parigi G, Mastarone DJ, Manus LM, Lilley LM, Preslar AT, Waters EA, Filicko A, Luchinat C, Ho D, Meade TJ. Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field. Nano Lett. 2016 Dec 14;16(12):7551-7564. https://doi.org/10.1021/acs.nanolett.6b03378. Epub 2016 Nov 15. PubMed PMID:27960515; PubMed Central PMCID: PMC5482002.
    SPACE
  5. Ravi D, Beheshti A, Abermil N, Passero F, Sharma J, Coyle M, Kritharis A, Kandela I, Hlatky L, Sitkovsky MV, Mazar A, Gartenhaus RB, Evens AM. Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma. Cancer Res. 2016 Jun 1;76(11):3319-31. https://doi.org/10.1158/0008-5472.can-15-2477. Epub 2016 Mar 17.
    SPACE
  6. Zhang ZM, Duan X, Yao S, Wang Z, Lin Z, Li YG, Long LS, Wang EB, Lin W. Cation-mediated optical resolution and anticancer activity of chiral polyoxometalates built from entirely achiral building blocks. Chem Sci. 2016 Jul 1;7(7):4220-4229. https://doi.org/10.1039/c5sc04408a. Epub 2016 Mar 9. PubMed PMID:30155068; PubMed Central PMCID: PMC6013930.

2015 

  1. Azarin SM, Yi J, Gower RM, Aguado BA, Sullivan ME, Goodman AG, Jiang EJ, Rao SS, Ren Y, Tucker SL, Backman V, Jeruss JS, Shea LD. In vivo capture and label-free detection of early metastatic cells. Nat Commun. 2015 Sep 8;6:8094. doi: 10.1038/ncomms9094. PubMed PMID: 26348915; PubMed Central PMCID: PMC4563812.
    SPACE
  2. Aguado BA, Wu JJ, Azarin SM, Nanavati D, Rao SS, Bushnell GG, Medicherla CB, Shea LD. Secretome identification of immune cell factors mediating metastatic cell homing. Sci Rep. 2015 Dec 4;5:17566. doi: 10.1038/srep17566. PubMed PMID:26634905; PubMed Central PMCID: PMC4669442.
    SPACE
  3. Dalva-Aydemir S, Bajpai R, Martinez M, Adekola KU, Kandela I, Wei C, Singhal S, Koblinski JE, Raje NS, Rosen ST, Shanmugam M. Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. Clin Cancer Res. 2015 Mar 1;21(5):1161-71. doi: 10.1158/1078-0432.CCR-14-1088.
    SPACE
  4. Duan X, Liu D, Chan C, Lin W. Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment. Small. 2015 Aug 26;11(32):3962-72. doi: 10.1002/smll.201500288. Epub 2015 May 12. PubMed PMID: 25963931; PubMed Central PMCID: PMC4635029
    SPACE
  5. Hartlieb KJ, Witus LS, Ferris DP, Basuray AN, Algaradah MM, Sarjeant AA, Stern CL, Nassar MS, Botros YY, Stoddart JF. Anticancer activity expressed by a library of 2,9-diazaperopyrenium dications. ACS Nano. 2015 Feb 24;9(2):1461-70. doi:10.1021/nn505895j. Epub 2015 Jan 23. PubMed PMID: 25555133; PubMed Central PMCID:PMC4344210.
    SPACE
  6. Kandela I, Jin HY, Owen K; Reproducibility Project: Cancer Biology.. Registered report: BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Elife. 2015 Jun 25;4:e07072. doi: 10.7554/eLife.07072.
    SPACE
  7. Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, Kessler JA, Peter ME, Mirkin CA, Stegh AH. miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma. Genes Dev. 2015 Apr 1;29(7):732-45.doi: 10.1101/gad.257394.114. PubMed PMID: 25838542; PubMed Central PMCID: PMC4387715.
    SPACE
  8. Swanson KI, Clark PA, Zhang RR, Kandela IK, Farhoud M, Weichert JP, Kuo JS. Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection. Neurosurgery. 2015 Feb;76(2):115-23; discussion 123-4. doi:10.1227/NEU.0000000000000622.

2014 

  1. Carney CE, MacRenaris KW, Mastarone DJ, Kasjanski DR, Hung AH, Meade TJ. Cell labeling via membrane-anchored lipophilic MR contrast agents. Bioconjug Chem. 2014 May 21;25(5):945-54. doi: 10.1021/bc500083t. Epub 2014 May 9. PubMed PMID:24787689; PubMed Central PMCID: PMC4033656.
    SPACE
  2. Dam DH, Culver KS, Kandela I, Lee RC, Chandra K, Lee H, Mantis C, Ugolkov A, Mazar AP, Odom TW. Biodistribution and in vivo toxicity of aptamer-loaded gold nanostars. Nanomedicine. 2015 Apr;11(3):671-9. doi: 10.1016/ j.nano. 2014.10.005. Epub 2014 Nov 18.
    SPACE
  3. He C, Liu D, Lin W. Self-assembled nanoscale coordination polymers carrying siRNAs and cisplatin for effective treatment of resistant ovarian cancer. Biomaterials. 2015 Jan;36:124-33. doi: 10.1016/j.biomaterials.2014.09.017. Epub 2014 Oct 12. PubMed PMID: 25315138; PubMed Central PMCID: PMC4252980.
    SPACE
  4. Ravi D, Bhalla S, Gartenhaus RB, Crombie J, Kandela I, Sharma J, Mazar A, Evens AM. The novel organic arsenical darinaparsin induces MAPK-mediated and SHP1-dependent cell death in T-cell lymphoma and Hodgkin lymphoma cells and human xenograft models. Clin Cancer Res. 2014 Dec 1;20(23):6023-33. doi:10.1158/1078-0432.CCR-14-1532. Epub 2014 Oct 14.
    SPACE
  5. Weichert JP, Clark PA, Kandela IK, Vaccaro AM, Clarke W, Longino MA, Pinchuk AN, Farhoud M, Swanson KI, Floberg JM, Grudzinski J, Titz B, Traynor AM, Chen HE,Hall LT, Pazoles CJ, Pickhardt PJ, Kuo JS. Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75. doi: 10.1126/scitranslmed.3007646. PubMed PMID: 24920661;

2013 

  1. Ahn RW, Barrett SL, Raja MR, Jozefik JK, Spaho L, Chen H, Bally MB, Mazar AP, Avram MJ, Winter JN, Gordon LI, Shea LD, O’Halloran TV, Woodruff TK. Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo. PLoS One. 2013;8(3):e58491. doi: 10.1371/journal.pone.0058491. Epub 2013 Mar 20. PubMed PMID: 23526987; PubMed Central PMCID: PMC3603968.
    SPACE
  2. Farmer RL, Scheidt KA. A Concise Enantioselective Synthesis and Cytotoxic Evaluation of the Anticancer Rotenoid Deguelin Enabled by a Tandem Knoevenagel/Conjugate Addition/Decarboxylation Sequence. Chem Sci. 2013 Aug;4(8):3304-3309. https://pubs.rsc.org/en/content/articlelanding/2013/sc/c3sc50424g. PubMed PMID: 24101971; PubMed Central PMCID: PMC3790643.
    SPACE
  3. Miodragović ĐU, Quentzel JA, Kurutz JW, Stern CL, Ahn RW, Kandela I, Mazar A, O’Halloran TV. Robust structure and reactivity of aqueous arsenous acid-platinum(II) anticancer complexes. Angew Chem Int Ed Engl. 2013 Oct 4;52(41):10749-52. doi: 10.1002/anie.201303251. Epub 2013 Aug 22.